This vehicle is no longer listed, so the estimate starts from $40,493 — the typical market price for this build. Move the numbers to match your own loan.

Vehicle price

Down payment

10% down

Interest rate (APR)

7.0% is a typical rate for a well-qualified buyer — use your own quote if you have one.

Loan term

Estimated monthly payment

$722

per month

60 months · 7.0% APR · $4,049 down

Amount financed

$36,444

Total interest

$6,876

Estimate only. Excludes tax, title, registration and dealer fees, and assumes a fixed-rate loan with equal monthly payments. Your actual rate depends on your credit and lender.

Decoded from the VIN

NHTSA build data for 2T2HGMDA7MC059840

Trim

450H

Engine

3.5L · V6

Horsepower

259

Drivetrain

4WD/4-Wheel Drive/4x4

Body

Sport Utility Vehicle (SUV)/Multi-Purpose Vehicle (MPV)

Fuel

Gasoline

Doors

Model year

2021

Made by

TOYOTA MOTOR MANUFACTURING CANADA

Full factory specs for this build →

✓ Backup camera
✓ Blind-spot monitor
✓ Lane departure
✓ ABS
✓ Electronic stability

Fuel economy (EPA)

Combined

MPG

City

MPG

Highway

MPG

$1,550 /yr est. fuel

Assumes 15,000 miles a year at $3.10/gallon and 30 MPG combined.

5-year cost to own

Beyond the sticker: what this 2021 Lexus RX450 likely costs over five years at 15,000 mi/yr.

Depreciation $14,248

Fuel $7,750

Insurance $9,050

Maintenance & repairs $4,312

Total, 5 years $35,360

Estimate — insurance and taxes vary by driver and state.

Model-level data for the 2021 Lexus RX450 from EPA fueleconomy.gov, refreshed September 1, 2026.

How it compares to rivals

Median asking price for comparable body styles listed near this car

Model	Median price	For sale nearby	vs this car
2021 Lexus RX 450H (this car)	$40,493	32	—
2021 Tesla Model Y	$20,449	22	−$20,044
2023 Nissan Rogue	$20,995	19	−$19,498
2019 Jeep Grand Cherokee	$18,496	16	−$21,997
2022 Acura MDX	$33,491	14	−$7,002
2023 Honda CR-V	$22,433	11	−$18,060