2022 Mercedes-Benz E-Class prices in the U.S.
The median pre-owned asking price for a 2022 Mercedes-Benz E-Class in the U.S. is $38,733 based on 247 pre-owned listings (of 352 total).
As of September 6, 2026, the median asking price for a used 2022 Mercedes-Benz E-Class in the U.S. is $38,733, based on 247 active dealer listings tracked by VinAssessment.
◷ Updated September 6, 2026 ▤ 352 active dealer listings, refreshed daily
Typical: $34,054–$47,934 — the middle half of 352 asking prices
Why the wide range? Price depends mostly on configuration and mileage — see below. This spread covers the middle 96% of asking prices: we exclude the cheapest and priciest 2% (payment-priced ads, typos, salvage) so outliers don't distort it.
What moves the price on a 2022 Mercedes-Benz E-Class
The $34,054–$47,934 typical range isn't randomness — three factors explain most of it:
The E350 typically asks $34,233, while the AMG E53 asks $53,129 — same year, same market.
Asking prices run about $42,992 under 15K miles and fall to $24,542 over 105K miles — roughly $1,800 for every 10,000 miles.
The same car typically asks $35,778 in Oklahoma but $51,250 in Minnesota.
Find your mileage and trim in the configurator below.
Configure the exact car
Modelled from 175 real asking prices, adjusted for mileage and location. Not a formal appraisal.
What would a 2022 Mercedes-Benz E-Class cost per month?
Estimate the monthly payment on a $34,233 vehicle. Move the numbers to match your own loan.
Estimate only. Excludes tax, title, registration and dealer fees, and assumes a fixed-rate loan with equal monthly payments. Your actual rate depends on your credit and lender.
2022 Mercedes-Benz E-Class: a fair price for your mileage
A 2022 Mercedes-Benz E-Class sheds roughly $1,800 for every 10,000 miles. Find your mileage below.
Fair price by mileage and trim
| Mileage | All listings | E350 | E450 | AMG E53 |
|---|---|---|---|---|
| Under 15K miles | $42,992 | $39,943 | $52,153 | $62,312 |
| 15K–30K miles | $40,541 | $36,338 | $48,687 | $55,795 |
| 30K–45K miles | $40,987 | $34,209 | $43,346 | $52,968 |
| 45K–60K miles | $34,765 | $31,703 | $38,814 | $50,694 |
| 60K–75K miles | $36,386 | $29,821 | $38,178 | $41,267 |
| 75K–90K miles | $35,290 | $28,874 | — | $42,340 |
| Over 105K miles | $24,542 | $23,029 | — | — |
Medians of live asking prices per band and version; “—” means fewer than 3 matching listings. National data.
Fair price by mileage — all versions combined
| Mileage ⓘ | Based on ⓘ | Fair price ⓘ | Typical range ⓘ |
|---|---|---|---|
| Under 15K miles | 28 listings | $42,992 | $40K–$57K |
| 15K–30K miles | 85 listings | $40,541 | $36K–$54K |
| 30K–45K miles | 120 listings | $40,987 | $35K–$48K |
| 45K–60K miles | 69 listings | $34,765 | $32K–$47K |
| 60K–75K miles | 32 listings | $36,386 | $30K–$40K |
| 75K–90K miles | 10 listings | $35,290 | $28K–$42K |
| Over 105K miles | 6 listings | $24,542 | $23K–$31K |
Same trim and condition assumed — mileage is the biggest lever after configuration.
2022 Mercedes-Benz E-Class: price by trim
| Trim | Based on ⓘ | Median price ⓘ | Typical range ⓘ | Where it sits ⓘ |
|---|---|---|---|---|
| E350 | 175 listings | $34,233 | $32K–$36K | |
| E450 | 83 listings | $42,703 | $40K–$47K | |
| AMG E53 | 80 listings | $53,129 | $48K–$57K | |
| Other trims | 11 listings | $48,539 | — |
Live 2022 Mercedes-Benz E-Class listings, priced by VIN
Every VIN links to a full market report: decode, active listings and the local price band. Shop 2021–2023 Mercedes-Benz E-Class listings on VehiSales →.
Price history
Median asking price by month · shaded band is the typical range (25th–75th percentile)
The median listing price for a 2022 Mercedes-Benz E-Class is $39,043 (September 2026) — down 5.0% from $41,110 in September 2025.
Monthly price table
| Month | Median price | Typical range | Vehicles listed |
|---|---|---|---|
| September 2026 | $39,043 | $35K–$47K | 155 |
| August 2026 | $38,535 | $34K–$47K | 397 |
| July 2026 | $38,736 | $35K–$48K | 428 |
| June 2026 | $38,888 | $35K–$46K | 388 |
| May 2026 | $38,886 | $35K–$45K | 383 |
| April 2026 | $39,985 | $36K–$47K | 369 |
| March 2026 | $39,600 | $36K–$47K | 511 |
| February 2026 | $39,800 | $35K–$46K | 539 |
| January 2026 | $39,586 | $35K–$46K | 510 |
| December 2025 | $39,900 | $35K–$48K | 368 |
| November 2025 | $39,996 | $36K–$47K | 254 |
| October 2025 | $40,000 | $37K–$47K | 247 |
| September 2025 | $41,110 | $38K–$46K | 212 |
2022 Mercedes-Benz E-Class prices by state
Listed this year counts every 2022 Mercedes-Benz E-Class first listed in 2026 (sold and active), with currently active cars as a floor. Typical price is the median of each car's latest asking price — or the average of active listings where this-year data is thin.
Factory configurations of the 2022 Mercedes-Benz E-Class
11 factory configurations left the plant as a 2022 Mercedes-Benz E-Class — the most common are below, each decoded into its own build sheet from the VIN pattern.
- E450 4MATIC ALL Terrain 3L 6cyl AWD $48,895
- E450 4MATIC 3L 6cyl AWD $41,360
- AMG E53 3L 6cyl AWD $62,312
- E450 4MATIC 3L 6cyl AWD $40,766
- AMG E53 3L 6cyl AWD $52,419
- E450 4MATIC 3L 6cyl AWD $56,403
- E350 2L 4cyl RWD $33,998
- E450 3L 6cyl RWD $55,940
- E450 3L 6cyl RWD $42,300
- AMG E53 3L 6cyl AWD $50,146
- E350 4MATIC 2L 4cyl AWD $34,765
All 11 factory configurations of the 2022 Mercedes-Benz E-Class →
Keep exploring E-Class prices
2022 Mercedes-Benz E-Class · $39,057 typical · 352 listingsOther Mercedes-Benz E-Class years
More 2022 Mercedes-Benz prices
Own a 2022 Mercedes-Benz E-Class? See what it's worth →
Frequently asked questions
Why do 2022 Mercedes-Benz E-Class prices range from $25,999 to $60,875?
The spread comes down to configuration and mileage: higher-mileage, base-configuration examples sit near the low end, while low-mileage and premium configurations reach the top. Half of all listings fall between $34,054 and $47,934 — see the mileage and trim breakdowns above for where a specific vehicle lands.
How much should mileage change the price of a 2022 Mercedes-Benz E-Class?
Expect roughly $1,800 less for every 10,000 miles on the odometer. A 60K-mile example should cost about $5,400 less than a 30K-mile one of the same trim — check the fair-price-by-mileage table above for your band.
How many 2022 Mercedes-Benz E-Class are for sale right now?
352 in total. Counts refresh daily from live dealer inventory.
How we calculate these prices
We track 352 active listings for this vehicle across dealer sites nationwide, updated every day. Average and median are computed from real asking prices on live listings. We exclude the top and bottom 2% of prices to reduce the influence of extreme values. This does not verify title status or guarantee that every erroneous listing is excluded. Prices reflect dealer asking prices — not final sale prices — and exclude taxes, fees, and incentives. Trim and mileage move the price more than any other factor; see the breakdowns above.
Want the original factory equipment and MSRP behind a specific car? See the factory window sticker for this E-Class →
Shopping for this car?
Check individual VINs before you buy — decode the exact trim and mileage, see every active listing, and how each price compares to the local market.